蝙蝠葛苏林碱对映异构体的合成
Synthesis of Antipode of Daurisoline
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摘要: 蝙蝠葛苏林碱属双苄基四氢异喹啉类生物碱,存在于防己科植物蝙蝠葛的根茎中,由郑锡文等分离得到,并证明结构。华维一等全合成了蝙蝠葛苏林碱并验证了结构。近几年来的药理研究发现,此生物碱为较强的Ca离Abstract: Daurisoline has been isolated from the plant Mcnispermum dauricum DC. The present investigation describes the total synthesis of antipode of Daurisoline via the optical active compounds (+)-1-(4-hydroxybenzyl)-2-methyl-6, 7-dimethoxy-1, 2, 3, 4-tetrahydro
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