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重组菌包含体中白细胞介素—2的分离[J]. 中国药科大学学报, 1991, (4): 246-248.
引用本文: 重组菌包含体中白细胞介素—2的分离[J]. 中国药科大学学报, 1991, (4): 246-248.
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Study on the Preparation and Their Propertives of Recombinant Interleukin-2 Inclusion Bodies[J]. Journal of China Pharmaceutical University, 1991, (4): 246-248.
Citation: Study on the Preparation and Their Propertives of Recombinant Interleukin-2 Inclusion Bodies[J]. Journal of China Pharmaceutical University, 1991, (4): 246-248.
shu

重组菌包含体中白细胞介素—2的分离

Study on the Preparation and Their Propertives of Recombinant Interleukin-2 Inclusion Bodies

    摘要
  • 摘要: 白细胞介素-2(IL-2)是调节免疫功能的淋巴因子。重组白细胞介素-2(rIL-2)的表达成功。为IL-2的基础研究和临床应用提供了条件。由于rIL-2在细菌中的高效表达,其形成包含体存在细菌胞浆中,难以溶解,给纯化工作带

     

    Abstract: Recombinant interleukin-2 (rIL-2) expressed by E. Coli appears in the form of undissolvable and polymeric inclusion bodies in the E. Coli cytoplasm. During the process of purification, the purity of rIL-2 existing in inclusion bodies was raised by dissolv

     

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