青霉素结合蛋白测定技术的研究

青霉素结合蛋白测定技术的研究[J]. 中国药科大学学报, 1991, (5): 308-310.

引用本文:

青霉素结合蛋白测定技术的研究[J]. 中国药科大学学报, 1991, (5): 308-310.

Detection of Penicillin-Binding Protein[J]. Journal of China Pharmaceutical University, 1991, (5): 308-310.

Citation:

Detection of Penicillin-Binding Protein[J]. Journal of China Pharmaceutical University, 1991, (5): 308-310.

Detection of Penicillin-Binding Protein

摘要: 当前,细菌耐药性问题日趋严重,给临床治疗带来困难,对β-内酰胺类抗生素而言,某些菌青霉素结合蛋白(PBPs)改变造成的耐药性,是β-内酰胺类抗生素的特点。一般细菌的PBPs

Abstract: A method is described for detecting tritium-labelled penicillin-binding proteins (PBPs) of Streptococcus pneumoniae. The samples of PBPs were obtained using whole organisms treated with ~3H-benzyl-penicillin. Sodium lauryl sarcosinate (Sarkosyl) was fou

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