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阿昔洛韦的改良合成法[J]. 中国药科大学学报, 1992, (1): 43-44.
引用本文: 阿昔洛韦的改良合成法[J]. 中国药科大学学报, 1992, (1): 43-44.
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An Improved Synthesis of Acyclovir[J]. Journal of China Pharmaceutical University, 1992, (1): 43-44.
Citation: An Improved Synthesis of Acyclovir[J]. Journal of China Pharmaceutical University, 1992, (1): 43-44.
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阿昔洛韦的改良合成法

An Improved Synthesis of Acyclovir

    摘要
  • 摘要: 阿昔洛韦(无环鸟苷,acyclovir)是有效的抗病毒药。化学名为9-(2-羟乙氧基)甲基鸟嘌呤(1)。该药在体外对Ⅰ型及Ⅱ型单纯疱疹及带状水豆病毒高度有效,而对哺乳动物宿主

     

    Abstract: The present paper deals with an improved synthesis of acyelovir from guanine by aeetylation, condensation and hydrolysis with overall yield being 69.50%.

     

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