中药雷公藤的毒代动力学研究

中药雷公藤的毒代动力学研究[J]. 中国药科大学学报, 1992, (1): 25-26.

引用本文:

中药雷公藤的毒代动力学研究[J]. 中国药科大学学报, 1992, (1): 25-26.

Study on Toxicokinetics of Crude Extract From Tripterygiurn wilfordii[J]. Journal of China Pharmaceutical University, 1992, (1): 25-26.

Citation:

Study on Toxicokinetics of Crude Extract From Tripterygiurn wilfordii[J]. Journal of China Pharmaceutical University, 1992, (1): 25-26.

Study on Toxicokinetics of Crude Extract From Tripterygiurn wilfordii

摘要: 应用两次给药的急性毒性法测定了雷公藤制剂中有毒成分的毒代动力学参数,结果小鼠体内半衰期为28.4 h。

Abstract: Tripterygium wilfordii (TW) is an important herbal drug, its extract has been used to treat auto-immune diseases such as lupus erythematosus, rheumatoid arthritis etc. Over-dose of the drug showed significant toxic effects which led to damages of heart, k

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