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氯噁唑仑体内代谢物7-氯-5-邻氯苯基-1,3-二氢-1,4-苯骈二氮杂-2-酮的合成[J]. 中国药科大学学报, 1993, (3): 180-181.
引用本文: 氯噁唑仑体内代谢物7-氯-5-邻氯苯基-1,3-二氢-1,4-苯骈二氮杂-2-酮的合成[J]. 中国药科大学学报, 1993, (3): 180-181.
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Synthesis of Metablism Product of Cloxazolam 7-Chloro-5-o-Chlorophenyl-1,3-Dihydro-1,4-Benzodiazepin-2-One[J]. Journal of China Pharmaceutical University, 1993, (3): 180-181.
Citation: Synthesis of Metablism Product of Cloxazolam 7-Chloro-5-o-Chlorophenyl-1,3-Dihydro-1,4-Benzodiazepin-2-One[J]. Journal of China Pharmaceutical University, 1993, (3): 180-181.
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氯噁唑仑体内代谢物7-氯-5-邻氯苯基-1,3-二氢-1,4-苯骈二氮杂-2-酮的合成

Synthesis of Metablism Product of Cloxazolam 7-Chloro-5-o-Chlorophenyl-1,3-Dihydro-1,4-Benzodiazepin-2-One

    摘要
  • 摘要: 氯噁唑仑(1)为苯骈二氮革类抗焦虑药,用于缓解由于紧张、不安和疲劳等情绪障碍引起的神经症状和自律神经症状,更年期综合症,月经前紧张、月经困难等疾病。它与

     

    Abstract: The metablism product of cloxazolam 7-chloro-5-o-chlorophenyl-1, 3-dihydro-1, 4-benzodiazepin-2-one (2) was prepared by 2, 5-dichloro-2-bromoacetamidobenzophenone, undergoing idonization, aminazition and cyclolization.

     

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