氯噁唑仑体内代谢物7-氯-5-邻氯苯基-1,3-二氢-1,4-苯骈二氮杂-2-酮的合成
Synthesis of Metablism Product of Cloxazolam 7-Chloro-5-o-Chlorophenyl-1,3-Dihydro-1,4-Benzodiazepin-2-One
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摘要: 氯噁唑仑(1)为苯骈二氮革类抗焦虑药,用于缓解由于紧张、不安和疲劳等情绪障碍引起的神经症状和自律神经症状,更年期综合症,月经前紧张、月经困难等疾病。它与Abstract: The metablism product of cloxazolam 7-chloro-5-o-chlorophenyl-1, 3-dihydro-1, 4-benzodiazepin-2-one (2) was prepared by 2, 5-dichloro-2-bromoacetamidobenzophenone, undergoing idonization, aminazition and cyclolization.
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Keywords:
- Cloxazolam /
- Metablism product /
- Synthesis
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