阿扑棉酚六甲醚的卤代反应
Halogenation of Apogossypol Hexamethyl Ether
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摘要: 在合成雄性抗生育剂棉酚衍生物的研究中,以棉酚(1)为原料,去醛基后得到阿扑棉酚(2),再经甲基化生成阿扑棉酚六甲醚(3)。用NBS与阿扑棉酚六甲醚反应,在不同条件下分别得到两个萘环上溴代产物。当用两分Abstract: The male antifertility agent gossypol was converted via apogossypol into apogossypol hexamethyl ether. The free radical halogenation reactions of apogossypol hexamethyl ether were investigated using a variety of different reagents, catalysts and technique
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