7-氨基-3-乙烯基-3-头孢烯-4-羧酸的合成
Synthesis of 7-Amino-3-Vinyl-3-Cephem-4-Carboxylic Acid
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摘要: 7-氨基-3-乙烯基-3-头孢烯-4-羧酸是合成第三代口服头孢菌素—Cefixime和Cefdinir的关键母体。其合成方法有多种。根Abstract: 7-Amino-3-vinyl-3-cephem-4-carboxylic acid was synthesized from diphenylmethyl 7-phenylacetami-do-3-bromo-methyl-cephem-4-carboxylate s-oxide by Wittig reaction.
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