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La、Pr、Nd、Sm-洛美沙星配合物的制备及其抗菌活性[J]. 中国药科大学学报, 1993, (5): 308-310.
引用本文: La、Pr、Nd、Sm-洛美沙星配合物的制备及其抗菌活性[J]. 中国药科大学学报, 1993, (5): 308-310.
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Preparation and Antibacterical Activity of Four New Complexes Between La, Pr, Nd or Sm and Lomefloxacin[J]. Journal of China Pharmaceutical University, 1993, (5): 308-310.
Citation: Preparation and Antibacterical Activity of Four New Complexes Between La, Pr, Nd or Sm and Lomefloxacin[J]. Journal of China Pharmaceutical University, 1993, (5): 308-310.
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La、Pr、Nd、Sm-洛美沙星配合物的制备及其抗菌活性

Preparation and Antibacterical Activity of Four New Complexes Between La, Pr, Nd or Sm and Lomefloxacin

    摘要
  • 摘要: 在丙酮和水组成的混合溶剂中,合成了La、Pr、Nd、Sm-洛美沙星的四种新的配合物,通过元素分析和红外光谱确定了配合物的组成和配位形式。用系列试管稀释法测定了配合物的体外抗菌活性。结果表明。稀土-洛美沙星配合物的脂溶性好,稀土离子对配体洛美沙星的抗菌活性不产生抑制作用。

     

    Abstract: Four new complexes, ReL_2Cl_3(H_2O)_8(Re=La, Pr, Nd, Sm; L=lomefloxacin) were prepared and characterized by IR spectra. Their probable structures were determined respectively on the basis of the IR spectra. The primary experiment showed that the earth ion

     

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