柑桔素对硝苯地平光降解稳定作用的研究
Effect of Naringenin on Photo stability of Nifedipine
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摘要: 在３种缓冲溶液和４种ｐＨ值情况下研究了日光照射下柑桔素对硝苯地平光降解的影响。硝苯地平在ｐＨ７．５６，６．３９，５．５５和３．９９缓冲溶液中的半衰期（ｔ１／２）分别为７．４，７．６，７．１和６．０ｈ；当在相同缓冲溶液中加入等量柑桔素时，硝苯地平的ｔ１／２分别为４．１，１１．８，７．３和６．１ｈ；各种溶液中，硝苯地平的光解均为一级动力学过程。在和柑桔素混合时，硝苯地平最稳定的ｐＨ值是６．４左右。Abstract: Photo stability of nifedipine(NF) and effect of naringenin(NR) on photodecomposition of NF under three buffer solutions and four pH values were presented.When pH values were 7.56, 6.39 ,5.55,3.99, t 1/2 of NF were 7.4,7.6,7.1,6.0 h respectivel
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