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氟罗沙星注射液的研制及其配伍变化分析[J]. 中国药科大学学报, 1996, (3): 18-20.
引用本文: 氟罗沙星注射液的研制及其配伍变化分析[J]. 中国药科大学学报, 1996, (3): 18-20.
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Studies on Preparation of Fleroxacin Injection and Its Incompatibility[J]. Journal of China Pharmaceutical University, 1996, (3): 18-20.
Citation: Studies on Preparation of Fleroxacin Injection and Its Incompatibility[J]. Journal of China Pharmaceutical University, 1996, (3): 18-20.
shu

氟罗沙星注射液的研制及其配伍变化分析

Studies on Preparation of Fleroxacin Injection and Its Incompatibility

    摘要
  • 摘要: 将氟罗沙星用天门冬氨酸调节ｐＨ直接配成注射液，采用高效液相色谱法进行含量测定，经稳定性试验表明，该注射液质量稳定。本品与氯化钠溶液配伍产生沉淀。该沉淀经紫外、红外、核磁、质谱等分析，并非为分解产物，而是氟罗沙星。

     

    Abstract: The fleroxacin(FLX) injection was prepared. The pH was adjusted with appropriate aspartic acid. A quantitative analysis was performed using HPLC. The stability of FLX injection under light and heat was studied by HPLC. After one years of storage, the cont

     

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