手性阳离子型Rh（Ⅰ）催化的高对映选择性的环化反应

摘要: 以阳离子型Ｒｈ＋（ＢＩＮＡＰ）ＣｌＯ－４为催化剂，４－取代－４－戊烯醛类化合物高对映选择性地（＞９９％ｅ．ｅ．）环化成３－取代环戊酮，而中性ＲｈＣｌ（ＢＩＮＡＰ）在４－取代－４－戊烯醛类的环化反应中，无催化活性。
- 对映选择性环化 /
- 阳离子铑配合物 /
- 中性铑配合物 /
- 手性配位体 /
- BINAP /
- 3-取代环戊酮
Abstract: Highly enantioselective cyclization (>99% e.e.) of 4 substituted 4 pentenals into 3 substituted cyclopentanone was achieved by using cationic Rh (BINAP) ClO - 4. 4 substituted 4 pentenals were not cyclized by the neutral RhCl(BINAP).
- enantioselective cyclization /
- cationic rhodium complex /
- neutral rhodium complex /
- chiral ligand /
- BINAP /
- 3 substituted cyclopentanone