N—酰化苄基四氢异喹啉类化合物的合成及其抗血小板聚集活性

N—酰化苄基四氢异喹啉类化合物的合成及其抗血小板聚集活性[J]. 中国药科大学学报, 1997, (5): 3+6-7.

引用本文:

N—酰化苄基四氢异喹啉类化合物的合成及其抗血小板聚集活性[J]. 中国药科大学学报, 1997, (5): 3+6-7.

Synthesis and Antiplatelet Aggregation of N Acylated Tetrahydrobenzylisoquinoline[J]. Journal of China Pharmaceutical University, 1997, (5): 3+6-7.

Citation:

Synthesis and Antiplatelet Aggregation of N Acylated Tetrahydrobenzylisoquinoline[J]. Journal of China Pharmaceutical University, 1997, (5): 3+6-7.

Synthesis and Antiplatelet Aggregation of N Acylated Tetrahydrobenzylisoquinoline

摘要: 合成了１４个Ｎ－酰化苄基四氢异喹啉化合物，并选择其中１０个化合物做了抗血小板聚集作用的体外试验，结果发现多数均具有一定的活性，为今后该类化合物的研究提供了参考数据。

Abstract: Fourteen N acylated tetrahydrobenzylisoquinoline derivatives were designed and synthesized of which 13 were not reported previously. The preliminary pharmacological tests showed that most compounds exhibited various degrees of antiplatelet aggregati

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