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喹诺酮类抗菌剂抗分支杆菌的QSAR研究——C-7位结构变化对活性的影响[J]. 中国药科大学学报, 1999, (1): 18-20.
引用本文: 喹诺酮类抗菌剂抗分支杆菌的QSAR研究——C-7位结构变化对活性的影响[J]. 中国药科大学学报, 1999, (1): 18-20.
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Studies on the Quantitative Structure activity Relationship of the Quinolone Antibacterials Against Mycobacteria:Effect of Structural Changes at C 7[J]. Journal of China Pharmaceutical University, 1999, (1): 18-20.
Citation: Studies on the Quantitative Structure activity Relationship of the Quinolone Antibacterials Against Mycobacteria:Effect of Structural Changes at C 7[J]. Journal of China Pharmaceutical University, 1999, (1): 18-20.
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喹诺酮类抗菌剂抗分支杆菌的QSAR研究——C-7位结构变化对活性的影响

Studies on the Quantitative Structure activity Relationship of the Quinolone Antibacterials Against Mycobacteria:Effect of Structural Changes at C 7

    摘要
  • 摘要: 用分子连接性指数法对一系列喹诺酮类化合物抗结核病分支杆菌的定量构效关系进行了研究。设计了４个新的化合物，预测它们具有高的抗菌活性。

     

    Abstract: The quantitative structure activity relationship(QSAR) of the quinolone antibacterials against mycobacteria was studied by the method of molecular connectivity. Four compounds were designed, which were expected to have high antibacterial activity aga

     

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