雷公藤甲素的半合成研究

雷公藤甲素的半合成研究[J]. 中国药科大学学报, 1999, (1): 15-17.

引用本文:

雷公藤甲素的半合成研究[J]. 中国药科大学学报, 1999, (1): 15-17.

Studies on the Semi synthesis of Triptolide[J]. Journal of China Pharmaceutical University, 1999, (1): 15-17.

Citation:

Studies on the Semi synthesis of Triptolide[J]. Journal of China Pharmaceutical University, 1999, (1): 15-17.

Studies on the Semi synthesis of Triptolide

摘要: 以雷酚内酯为原料，经甲基化、氧化、去甲基化、还原、环氧化等七步反应合成了雷公藤甲素。其结构经红外光谱、核磁共振光谱、质谱确证。

Abstract: Triptolide was semi synthesized by triptophenolide,which was a convenient starting material and was isolated from extracts of Tripterygium wilfordii ,through methylating,oxidation,demethylating,reduction and epoxidation reaction.This method promoted t

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