罗红霉素颗粒剂的制备及生物利用度研究

Preparation of Roxithromycin Granules and Study on Its Relative Bioavailability

摘要: 研制了罗红霉素颗粒剂：以罗力得片为对照，采用微生物法进行了健康人体血药浓度测定，考察了罗红霉素颗粒剂的药动学特性。结果表明，罗红霉素颗粒剂与对照品为生物等效制剂。
- 罗红霉素 /
- 药物动力学 /
- 生物利用度 /
- 微生物检定法 /
- 颗粒剂
Abstract: Roxithromycin granules were prepared. The pharmacokinetics and relative bioavailability of roxithromycin granules were investigated at the oral dose of 300 mg in 9 healthy volunteers.Drug concentrations in plasma were assayed by microbiology m
- Roxithromycin /
- Granules /
- Pharmacokinetics /
- Bioavaility /
- Microbiology method