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抗癌新药伊立替康有关物质的研究[J]. 中国药科大学学报, 1999, (3): 36-38.
引用本文: 抗癌新药伊立替康有关物质的研究[J]. 中国药科大学学报, 1999, (3): 36-38.
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Studies on Correlated Substance of New Anticancer Drug Irinotecan[J]. Journal of China Pharmaceutical University, 1999, (3): 36-38.
Citation: Studies on Correlated Substance of New Anticancer Drug Irinotecan[J]. Journal of China Pharmaceutical University, 1999, (3): 36-38.
shu

抗癌新药伊立替康有关物质的研究

Studies on Correlated Substance of New Anticancer Drug Irinotecan

    摘要
  • 摘要: 建立了反相高效液相色谱及薄层色谱分离分析方法,对伊立替康样品中有关物质的组成成分进行了研究。初步确证样品中的主要杂质为SN38 和伊立替康羟酸。

     

    Abstract: RP HPLC and TLC methods were developed for studies on correlated substance of new anticancer drug irinotecan, a water soluble derivative of camptothecin, with potent anti cancer activity. It is preliminarily validated that SN 38 and CPT 11 carboxily a

     

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