班布特罗的合成

The Synthesis of Ba m buterol

摘要: 班布特罗作为支气管解痉药具有作用时效长，副作用特别是对心血管系统的副作用非常微弱等优点。作者对文献合成方法进行了合理的改进，避免使用苄基保护的特丁胺和加压氢化还原脱苄基，简化了实验步骤和原材料，反应总收率比文献收率提高了１．５倍，达到５６％，较大地降低了生产成本。

Abstract: Bambuterol ,as a bronchodilator ,exhibits the prolonged duration of bronchospasmolytic activity and verylow side effects especially to heart blood vessal system . The synthetic method of bambuterol was improved , inimproved method the compound of t bu