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复方美沙芬片的毛细管电泳快速分析[J]. 中国药科大学学报, 2001, (4): 38-40.
引用本文: 复方美沙芬片的毛细管电泳快速分析[J]. 中国药科大学学报, 2001, (4): 38-40.
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Simultaneous Determination of Dextromethorphen and Pseudoephedrine in Compound t ablets by HPCE[J]. Journal of China Pharmaceutical University, 2001, (4): 38-40.
Citation: Simultaneous Determination of Dextromethorphen and Pseudoephedrine in Compound t ablets by HPCE[J]. Journal of China Pharmaceutical University, 2001, (4): 38-40.
shu

复方美沙芬片的毛细管电泳快速分析

Simultaneous Determination of Dextromethorphen and Pseudoephedrine in Compound t ablets by HPCE

    摘要
  • 摘要: 目的建立了毛细管电泳快速测定复方美沙芬片中有效成分含量的方法,讨论了硼酸盐浓度对分离选择性的影响.方法在40cm×50μm的未涂层石英毛细管柱上,以10mmol/L硼酸盐为缓冲液,214nm为测定波长,10min之内用内标法测得伪麻黄碱和美沙芬的含量.结果两组分含量在98.0%～101%之间,线性范围分别为0.3～3.0mg/ml和0.1～1.0mg/ml,RSD小于3%.结论该方法可用于复方美沙芬片的质量控制.

     

    Abstract: AIM A HPCE method is developed which can simultaneously deter mi ne for the separation of dextromethorphen and pseudoephedrine in tablets. The i nfluence of borate buffers on the electrophoretic behavior of pseudoephedrine wa s investigated. METHOD\ This

     

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