- 中国精品科技期刊
- 中国高校百佳科技期刊
- 中国中文核心期刊
- 中国科学引文数据库核心期刊
| Citation: |
CHENG Haibo, XU Bin, ZHANG Huibin, ZHOU Jinpei. Synthetic process of antitumor drug dacomitinib[J]. Journal of China Pharmaceutical University, 2014, 45(2): 165-169. DOI: 10.11665/j.issn.1000-5048.20140206
|
| [1] |
Fry DW,Kraker AJ,McMichael A,et al.A specific inhibitor of the epidermal growth factor receptor tyrosine kinase[J].Science,1994,265(5 175):1 093-1 095.
|
| [2] |
Engelman JA, Zejnullahu K, Gale CM, et al. PF00299804,an irreversible pan-ERBB inhibitor,is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib[J].Cancer Res,2007,67(24):11 924-11 932.
|
| [3] |
Ercan D,Zejnullahu K,Yonesaka K,et al.Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor[J].Oncogene,2010,29(16):2 346-2 356.
|
| [4] |
Rewcastle GW,Denny W A,Bridges AJ,et al.Tyrosine kinase inhibitors.5.Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]-and 4-(phenylamino)quinazolines as potent adenosine 5′-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor[J].J Med Chem,1995,38(18):3 482-3 487.
|
| [5] |
Kalous O,Conklin D,Desai AJ,et al.Dacomitinib(PF-00299804),an irreversible Pan-HER inhibitor,inhibits proliferation of HER2-amplified breast cancer cell lines resistant to trastuzumab and lapatinib[J].Mol Cancer Ther,2012,11(9):1 978-1 987.
|
| [6] |
Wu J,Chen W,Xia G,et al.Design,Synthesis,and biological evaluation of novel conformationally constrained inhibitors targeting EGFR[J].ACS Med Chem Lett,2013,4(10):974-978.
|
| [7] |
Heuckmann,Johannes M,Rauh D,et al.Epidermal growth factor receptor(EGFR)signaling and covalent EGFR inhibition in lung cancer[J].J Clin Oncol,2012,30(27):3 417-3 420.
|
| [8] |
Brugger,Wolfram,Michael T.EGFR-TKI resistant non-small cell lung cancer(NSCLC):new developments and implications for future treatment[J].Lung Cancer,2012,77(1):2-8.
|
| [9] |
Barf, Tjeerd, Kaptein A. Irreversible protein kinase inhibitors: balancing the benefits and risks[J].J Med Chem,2012,55(14):6 243-6 262.
|
| [10] |
Bain J,Plater L,Elliott M,et al.The selectivity of protein kinase inhibitors:a further update[J].Biochem J,2007,408:297-315.
|
| [11] |
Minisci F,Recupero F,Cecchetto A,et al.Polar effects in free-radical reactions.A novel homolytic acylation of heteroaromatic bases by aerobic oxidation of aldehydes,catalysed by N-hydroxyphthalimide and Co salts[J].J Heterocyclic Chem,2003,40(2):325-328.
|
| [12] |
Kundu SK, Mahindaratne MPD,Quintero MV,et al.One-pot reductive cyclization to antitumor quinazoline precursors[J].Arkivoc,2008,2:33-42.
|
| [13] |
Lin GY,Yan WW,Chen XM,et al.Synthesis of(3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine:CN,200910103605.2[P].2011-01-05[2013-12-24] .
|
| [14] |
Fakhoury, Lee, Reed, et al. 4-phenylamino-quinazolin-6-yl-amides:US,7772243 B2[P].2010-08-10.
|
| [15] |
Lin KC,Mo GN.Synthesis of EGFR inhibitor dacomitinib:CN,201310245229.7[P].2013-09-18[2013-12-24] .
|
| [16] |
Roth HF,Li M,Jiang J,et al.Heck reaction and Stille coupling as the key steps in the synthesis of carbon-14-labeled gsk-3 inhibitor alsterpaullone[J].J Labelled Comp Radiopharm,2011,54(5):272-277.
|
| [17] |
Pospíil J,Potáek M.Microwave-assisted solvent-free intramolecular 1,3-dipolar cycloaddition reactions leading to hexahydrochromenopyrroles:scope and limitations[J].Tetrahedron,2007,63(2):337-346.
|
| [18] |
Khazaei A, Vaghei RG, Karkhanei E. Bromination of organic allylic compounds by using N,N′-dibromo-N,N′-1,2-ethane diyl bis(2,5-dimethyl benzene sulphonyl)amine[J].Synthetic Commun,2002,32(14):2 107-2 113.
|
| [1] | LI Xue, AI Yongling, HE Qunye, YANG Gongjun, WANG Jing. Detection of prostate specific antigen-based on dual signal amplified electrochemical immunoassay[J]. Journal of China Pharmaceutical University, 2018, 49(4): 433-440. DOI: 10.11665/j.issn.1000-5048.20180408 |
| [2] | SONG Fengjuan, AI Yongling, ZHONG Wenying, WANG Jing. Detection of copper ions and glutathione based on off-on fluorescent graphene quantum dots[J]. Journal of China Pharmaceutical University, 2018, 49(1): 87-92. DOI: 10.11665/j.issn.1000-5048.20180112 |
| [3] | ZHOU Weisai, WU Zimei, BAGULEY Bruce C., LI Caibin, ZHANG Wenli, LIU Jianping. Preparation of CI-921 mixed micelles and determination of its entrapment efficiency by method of dialysis and fitting[J]. Journal of China Pharmaceutical University, 2016, 47(5): 575-580. DOI: 10.11665/j.issn.1000-5048.20160512 |
| [4] | WU Mingming, FANG Lei, GOU Shaohua, CHEN Li. 以2-甲基-2-取代苯氧基丙酸为离去基团的铂(Ⅱ)配合物的合成、表征及细胞毒活性[J]. Journal of China Pharmaceutical University, 2013, 44(4): 303-306. DOI: 10.11665/j.issn.1000-5048.20130403 |
| [5] | Synthesis of violet-near-infrared-emitting quantum dots using N-acetyl-L-cysteine as ligand[J]. Journal of China Pharmaceutical University, 2010, 41(5): 456-461. |
| [6] | BESN System of Multi-channel Tail-artery Blood Pressure Measurement[J]. Journal of China Pharmaceutical University, 2004, (5): 80-83. |
| [7] | Preparation and Antibacterial Testing of dihydroxyaluminum sodium carbonate and its Tablet[J]. Journal of China Pharmaceutical University, 1998, (3): 84-86. |
| [8] | DISCUSSION OF STABILITY OF THE YIN-YANG EQUATION[J]. Journal of China Pharmaceutical University, 1987, (1): 40-44. |
| [9] | UV SPECTROPHOTOMETRIC ANALYSIS OF MULTICOMPONENT COMPLEX PREPARATION BY THE LEAST SQUARES AREA FITTING METHOD[J]. Journal of China Pharmaceutical University, 1986, (3): 201-207. |
| [10] | Dong Shanshi, Yang Jingrong, An Dengkui. DETERMINATION OF NONOXYNOL-9 IN THE CAPSHAPED CONTRACEPTIVE FILMS BY ORTHOGONAL POLYNOMIAL SPECTROPHOTOMETRY[J]. Journal of China Pharmaceutical University, 1982, (3): 57-58. |
Supported by: Beijing Renhe Information Technology Co., Ltd. 
Total visits：292734
DownLoad: