Self-assembled peptide:insights and biomedicine applications

ZHANG Chenyu; LI Xue; QIAN Hai; HUANG Wenlong

doi:10.11665/j.issn.1000-5048.20150219

Journal of China Pharmaceutical University > 2015 > 46(2): 250-256. > DOI: 10.11665/j.issn.1000-5048.20150219

ZHANG Chenyu, LI Xue, QIAN Hai, HUANG Wenlong. Self-assembled peptide:insights and biomedicine applications[J]. Journal of China Pharmaceutical University, 2015, 46(2): 250-256. DOI: 10.11665/j.issn.1000-5048.20150219

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Self-assembled peptide:insights and biomedicine applications

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Abstract

Self-assembled peptides occur via inter-molecular non-covalent assembly, spontaneity or triggering, and the formed nanostructures have been found to have certain features and functions which are not shown by the original peptide molecules or low-hierarchical molecules. There are growing attentions on the self-assembled peptide. This review provides detailed classifications of self-assembled peptides, i. e. , spontaneity and triggering, according to how the self-assemble responds or adjusts to outer environment. In addition, the summary offers potentials of their applications in biomedicine, such as anti-tumor and anti-bacterial medicine, drug carriers modifying pharmaceutical features of drugs, enhanced drug targeting, matrix as cell culture, tissue regeneration, and biomedicinal detection.
- self-assembled peptides,
- drug carrier,
- targeting,
- applications

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