Advances in taste-masking technology of oral paediatric medicine

TANG Linfang; ZHANG Ziqiang; SU Rina; HE Shuwang; YAO Jing

doi:10.11665/j.issn.1000-5048.20170202

Journal of China Pharmaceutical University > 2017 > 48(2): 135-141. > DOI: 10.11665/j.issn.1000-5048.20170202

TANG Linfang, ZHANG Ziqiang, SU Rina, HE Shuwang, YAO Jing. Advances in taste-masking technology of oral paediatric medicine[J]. Journal of China Pharmaceutical University, 2017, 48(2): 135-141. DOI: 10.11665/j.issn.1000-5048.20170202

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Advances in taste-masking technology of oral paediatric medicine

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Abstract

As children are extremely sensitive to the bad taste of medicine, they have poor compliance with the bitter medicine. It is of great importance to develop the approaches of taste masking for the research of paediatric drug formulations. Besides, taste masking technology is one of the main barrier to develop children pharmaceutic preparation. This article provides an overview of the advance in taste masking technology of oral paediatric medicine in recent years, and introduces five types of taste masking technology in terms of drug, preparation and the bitter taste transduction, including principle and characteristics of these approaches, as well as their application in formulations, so as to provide some references for the development of paediatric medicine.
- paediatric medicine,
- formulations,
- bitter,
- taste-masking technology

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