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SYNTHESIS OF CEFMENOXIME[J]. Journal of China Pharmaceutical University, 1985, (1): 1-3.
Citation: SYNTHESIS OF CEFMENOXIME[J]. Journal of China Pharmaceutical University, 1985, (1): 1-3.
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SYNTHESIS OF CEFMENOXIME

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  • Cefmenoxime was synthesized by a four-step method with overall yield of 35.80%. The conversion of 7-ACA to 7-ACT with 1-methyl-1H-tetrazole-5-thiol, the condensation of the side-chain 2-(2-chloroacetamidothiazol-4-yl)-(Z)-2-me- thoxyimino-acetic acid with
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