• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
YAO Jing, FAN Ying, ZHOU Jian-ping, LI Fei-yan. Advances on the study of new cationic polymers as gene vectors[J]. Journal of China Pharmaceutical University, 2011, 42(2): 176-181.
Citation: YAO Jing, FAN Ying, ZHOU Jian-ping, LI Fei-yan. Advances on the study of new cationic polymers as gene vectors[J]. Journal of China Pharmaceutical University, 2011, 42(2): 176-181.

Advances on the study of new cationic polymers as gene vectors

More Information
  • A successful gene therapy largely depends on the development of effective,secure and targeting delivery vectors.Compared to the viral vectors,the non-viral vectors have many advantages including lower cytotoxicity,the potential to be administered repeatedly with minimal host immune response,targetability,stability in storage and ease to produce in large quantities.Especially,cationic polymers were given greatly concern.The latest advances on the modification of the polymers to reduce the cytotoxicity,improve the stability and transfection efficiency of the complex,and achieve targeting delivery,are reviewed in this paper.
  • Related Articles

    [1]LIU Xinao, CHEN Qinying, CHEN Dali, TU Jiasheng, SUN Chunmeng. Charge shielding and targeted delivery strategies of cationic carriers[J]. Journal of China Pharmaceutical University, 2025, 56(3): 271-279. DOI: 10.11665/j.issn.1000-5048.2024121201
    [2]ZHANG Xinran, LI Bo, DI Bin. Advances in racemization of protein amino acid[J]. Journal of China Pharmaceutical University, 2017, 48(4): 407-415. DOI: 10.11665/j.issn.1000-5048.20170404
    [3]CHEN Xing, KANG Yang, WU Jun. Advances in biodegradable functional polymers based protein drug delivery system[J]. Journal of China Pharmaceutical University, 2017, 48(2): 142-149. DOI: 10.11665/j.issn.1000-5048.20170203
    [4]LIU Juan, ZHENG Xueqin, CHENG Linfeng, ZHANG Ying, GAO Yuan, ZHANG Jianjun. Effect of polymers on the formation thermodynamics of adefovir dipifoxil-saccharin cocrystal[J]. Journal of China Pharmaceutical University, 2015, 46(2): 194-200. DOI: 10.11665/j.issn.1000-5048.20150210
    [5]JIANG Hulin. Biocompatible polymers for gene delivery in cancer gene therapy[J]. Journal of China Pharmaceutical University, 2013, 44(5): 476-481. DOI: 10.11665/j.issn.1000-5048.20130518
    [6]LI Ying-huan, ZONG Li, ZHU Jia-bi. Formulation optimization of PEGylated cationic liposomes as siRNA delivery system[J]. Journal of China Pharmaceutical University, 2011, 42(5): 412-417.
    [7]XUE Qiao-ru, LIANG Wei-yang, CHEN Yu-kun. Determination of peptide contents of hepatocyte growth-promoting factor for injection by acid hydrolytic method[J]. Journal of China Pharmaceutical University, 2011, 42(4): 333-336.
    [8]LIN Zhong, LUO Zhong-qiu, DOU Jie, WANG Hui, QIU Wei-ran, CAO Jing, ZHOU Chang-lin. High RNA accumulation in Candida tropicalis is affected by specific growth rate and different medium composition[J]. Journal of China Pharmaceutical University, 2011, 42(2): 169-175.
    [9]YANG Yan, ZHU Jia-bi, ZHENG Chun-li, CHEN Sheng-jun. Preparation and characterization of aqueous polymer dispersions with high flexibility for coating[J]. Journal of China Pharmaceutical University, 2009, 40(4): 310-315.
    [10]APPLICATION OF CATIONIC SURFACTANT ON THE ACID DYE METHOD OF STRYCHNINE NITRATE INJECTIONS[J]. Journal of China Pharmaceutical University, 1988, (2): 141-144.

Catalog

    Article views (1988) PDF downloads (4394) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return