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HPLC法测定复方美沙芬缓释片的释放度和含量[J]. 中国药科大学学报, 1999, (5): 364-366.
引用本文: HPLC法测定复方美沙芬缓释片的释放度和含量[J]. 中国药科大学学报, 1999, (5): 364-366.
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Determination of in Vitro Release and Content of Dextrome thorphan Hydrobromide and Pseudoephedrine Hydrochloride Sustained-Release Tablets by HPLC[J]. Journal of China Pharmaceutical University, 1999, (5): 364-366.
Citation: Determination of in Vitro Release and Content of Dextrome thorphan Hydrobromide and Pseudoephedrine Hydrochloride Sustained-Release Tablets by HPLC[J]. Journal of China Pharmaceutical University, 1999, (5): 364-366.
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HPLC法测定复方美沙芬缓释片的释放度和含量

Determination of in Vitro Release and Content of Dextrome thorphan Hydrobromide and Pseudoephedrine Hydrochloride Sustained-Release Tablets by HPLC

    摘要
  • 摘要: 采用HPLC法测定复方美沙芬缓释片释放度和含量。该法采用YWG-C18色谱柱,以乙腈-醋酸钠溶液-高氨酸-三乙胺（40：60：0.5：0.1）为流动相,能同时测定制剂中伪麻黄碱和氢溴酸右美沙芬,精密度好,峰面积与浓度呈良好线性关系,回收率约100％,RSD＜1.5％。

     

    Abstract: Determination of release and content of compound dextromethorphan sustuined release tablets by HPLC was established. This stationary phase was YWG-C18, the mobile phase was composed of the mixture of acetonitrile and CH3COONa buffer. This condition for an

     

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