Citation: | CHEN Jianping, REN Xinsheng, SUN Zhonghua, GUO Zaiyu. Protective effects and mechanisms of breviscapine on endothelial cells[J]. Journal of China Pharmaceutical University, 2015, 46(5): 610-616. DOI: 10.11665/j.issn.1000-5048.20150516 |
[1] |
Lin LL,Liu AJ,Liu JG,et al.Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats[J].J Cardiovasc Pharmacol,2007,50(3):327-332.
|
[2] |
Qi XM,Wu GZ,Wu YG,et al.Renoprotective effect of breviscapine through suppression of renal macrophage recruitment in streptozotocin-induced diabetic rats[J].Nephron Exp Nephrol,2006,104(4):e147-157.
|
[3] |
Yan L,Huang H,Tang QZ,et al.Breviscapine protects against cardiac hypertrophy through blocking PKC-alpha-dependent signaling[J].J Cell Biochem,2010,109(6):1158-1171.
|
[4] |
Wang M, Zhang WB, Zhu JH, et al. Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway[J].Acta Pharmacol Sin,2009,30(8):1081-1091.
|
[5] |
Li Q,Wu JH,Guo DJ,et al.Suppression of diet-induced hypercholesterolemia by scutellarin in rats[J].Planta Med,2009,75(11):1203-1208.
|
[6] |
He M,Xue ZM,Li J,et al.Breviscapine inhibits high glucose-induced proliferation and migration of cultured vascular smooth muscle cells of rats via suppressing the ERK1/2 MAPK signaling pathway[J].Acta Pharmacol Sin,2012,33(5):606-614.
|
[7] |
Moldovan L,Mythreye K,Goldschmidt-Clermont PJ,et al.Reactive oxygen species in vascular endothelial cell motility.Roles of NAD(P)H oxidase and Rac1[J].Cardiovasc Res,2006,71(2):236-246.
|
[8] |
Hsieh HJ,Cheng CC,Wu ST,et al.Increase of reactive oxygen species(ROS)in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression[J].J Cell Physiol,1998,175(2):156-162.
|
[9] |
Steinberg D,Witztum JL.Oxidized low-density lipoprotein and atherosclerosis[J].Arterioscler Thromb Vasc Biol,2010,30:2311-2316.
|
[10] |
Wiesner P,Choi SH,Almazan F,et al. Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1:possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia[J].Circ Res,2010,107(1):56-65.
|
[11] |
Wagner AE,Ernst I,Iori R,et al.Sulforaphane but not ascorbigen,indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture[J].Exp Dermatol,2010,19(2):137-144.
|
[12] |
Chavakis E,Dernbach E,Hermann C,et al.Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway[J].Circulation,2001,103(16):2102-2107.
|
[13] |
Kotamraju S,Hogg N,Joseph J,et al.Inhibition of oxidized low-density lipoprotein-induced apoptosis in endothelial cells by nitric oxide.Peroxyl radical scavenging as an antiapoptotic mechanism[J].J Biol Chem,2001,276(20):17316-17323.
|
[14] |
Wang Y, Ji M, Chen L, et al. Breviscapine reduces acute lung injury induced by left heart ischemic reperfusion in rats by inhi-biting the expression of ICAM-1 and IL-18[J].Exp Ther Med,2013,6(5):1322-1326.
|
[15] |
Zhang H,Cai CZ,Zhang XQ,et al.Breviscapine attenuates acute pancreatitis by inhibiting expression of PKCα and NF-κB in pancreas[J].World J Gastroenterol,2011,17(14):1825-1830.
|
[16] |
Zhang DD,Hannink M.Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress[J].Mol Cell Biol,2003,23(22):8137-8151.
|
[17] |
Kobayashi A1,Kang MI,Okawa H,et al.Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2[J].Mol Cell Biol,2004,24(16):7130-7139.
|
[18] |
Jain AK,Bloom DA,Jaiswal AK.Nuclear import and export signals in control of Nrf2[J].J Biol Chem,2005,280(32):29158-29168.
|
[19] |
Dhakshinamoorthy S,Jaiswal AK.Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene[J].Oncogene,2001,20(29):3906-3917.
|
[20] |
Hayes JD,Chanas SA,Henderson CJ,et al.The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants,butylated hydroxyanisole and ethoxyquin[J].Biochem Soc Trans,2000,28(2):33-41.
|
[1] | LIU Linchen, XU Xiaoyan, SUN Chunmeng, YU Jirong, SHI Qing, SUN Junjun, PANG Dandan, WEI Feiran, LIU Xing. Ginkgolide B inhibits cell proliferation and promotes cell apoptosis of MH7A human fibroblast-like synoviocytes through PI3K/AKT pathway[J]. Journal of China Pharmaceutical University, 2025, 56(2): 216-224. DOI: 10.11665/j.issn.1000-5048.2024091403 |
[2] | QI Weiyan, XIA Chunlei, AN Roujin, Gao Xinmei, LI Dongping, XU Hanmei. Suppressive effect of lignans from Euphorbia neriifolia L.on esophageal squamous cancer cell[J]. Journal of China Pharmaceutical University, 2022, 53(1): 93-98. DOI: 10.11665/j.issn.1000-5048.20220114 |
[3] | SHEN Jie, ZHA Qian, GAO Xiangdong, CHEN Song. Construction of mutant NDUFS7 plasmid and its effects on neural cells[J]. Journal of China Pharmaceutical University, 2020, 51(5): 599-606. DOI: 10.11665/j.issn.1000-5048.20200512 |
[4] | WANG Dandan, KORAMAGAZI Arouna, MAO Yong, YU Feng. Rhein induces apoptosis in L-02 cells via reactive oxygen species-independent endoplasmic reticulum stress pathway[J]. Journal of China Pharmaceutical University, 2016, 47(2): 215-221. DOI: 10.11665/j.issn.1000-5048.20160215 |
[5] | QI Cuiling, ZHOU Xinlei, YE Jie, YANG Yang, ZHANG Qianqian, LI Jiangchao, WANG Lijing. Andrographolide induces Tb cell apoptosis by activating Caspase-3/PARP[J]. Journal of China Pharmaceutical University, 2013, 44(6): 559-562. DOI: 10.11665/j.issn.1000-5048.20130614 |
[6] | WANG Ping, SUN Li, LIN Sen-sen, YUAN Sheng-tao. Construction of endothelial cell three-dimension sprouting model[J]. Journal of China Pharmaceutical University, 2012, 43(1): 60-63. |
[7] | SHAO Jing-ping, ZHANG Shan-fei, CHEN Yuan-cheng, YANG Wen-liang, LIU Xiao-quan. Cellular uptake characteristics of salvianolic acid B in myocardial cells and blood vessel endothelial cells[J]. Journal of China Pharmaceutical University, 2009, 40(3): 263-268. |
[8] | Influence of Puerarin on Endogenous NOS Inhibitor of Human Umbilical Vein Endothelial Cells Cultured with Oxidized Low Density Lipoprotein[J]. Journal of China Pharmaceutical University, 2004, (4): 63-66. |
[9] | Protective Effects of MCl-186 on Apoptosis in PC12 Cells Induced by H2O2[J]. Journal of China Pharmaceutical University, 2004, (1): 62-66. |
[10] | Modulation of Crocin on [Ca2+ ]j in Cultured Bovine Aortic Endothelial Cells[J]. Journal of China Pharmaceutical University, 2002, (5): 92-94. |