Advances in biomimetic drug delivery systems based on platelet and platelet membrane

XU Jianpei; XU Qunwei; WANG Xiaoqi; XIN Hongliang

doi:10.11665/j.issn.1000-5048.20180603

Journal of China Pharmaceutical University > 2018 > 49(6): 653-659. > DOI: 10.11665/j.issn.1000-5048.20180603

XU Jianpei, XU Qunwei, WANG Xiaoqi, XIN Hongliang. Advances in biomimetic drug delivery systems based on platelet and platelet membrane[J]. Journal of China Pharmaceutical University, 2018, 49(6): 653-659. DOI: 10.11665/j.issn.1000-5048.20180603

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Advances in biomimetic drug delivery systems based on platelet and platelet membrane

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Abstract

Platelet is an important component of human blood, which plays a key role in the physiological and pathological processes. Recently, novel drug delivery system based on platelet and platelet membrane bionics attracted much attention. Compared to the traditional drug carriers, platelet and platelet membrane-based biomimetic drug delivery system has great performances in biocompatibility, longer circulation and stronger ability of targeting. This review presented the features, classifications, drug-loading and applications of platelet and platelet membrane-based biomimetic drug delivery systems, promoting their development and application in the future.
- blood platelets,
- platelet membrane,
- drug carriers,
- biomimetics,
- nano,
- drug delivery system

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