A new ester glycoside compound from <i>Cyclocarya paliurus</i>

FANG Siyang; ZHANG Xinggui; YE Yu; WANG Keqing; YAO Zhiren; HUANG Yaping; ZHANG Jian; QIN Yanhua; YIN Zhiqi

doi:10.11665/j.issn.1000-5048.20221209002

Journal of China Pharmaceutical University > 2023 > 54(1): 56-61. > DOI: 10.11665/j.issn.1000-5048.20221209002

FANG Siyang, ZHANG Xinggui, YE Yu, WANG Keqing, YAO Zhiren, HUANG Yaping, ZHANG Jian, QIN Yanhua, YIN Zhiqi. A new ester glycoside compound from Cyclocarya paliurus[J]. Journal of China Pharmaceutical University, 2023, 54(1): 56-61. DOI: 10.11665/j.issn.1000-5048.20221209002

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A new ester glycoside compound from Cyclocarya paliurus

1.
Department of Traditional Chinese Pharmaceutic, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198
2.
Jiangsu Provincial Academy of Traditional Chinese Medicine, Nanjing 210028
3.
China Tobacco Jiangsu Industrial Co., Ltd., Nanjing 210019, China

Funds: This study was supported by the National Natural Science Foundation of China (No.81872984), "Qing-Lan" Project of Jiangsu Higher Education Institutions, and the Science and Technology Project of China Tobacco Jiangsu Industrial Co., Ltd.(No.H202204)

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Received Date: December 08, 2022
Revised Date: March 02, 2023

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Abstract

Abstract

Chemical constituents of n-butanol part of ethanol extract from the leaves of Cyclocarya paliurus (Batalin) Iljinskaja were studied.Eight glycosides were separated and purified by silica gel, MCI, ODS, Sephadex LH-20 column chromatography and semi-preparative high-performance liquid chromatography.Based on the physicochemical properties and spectral data, these compounds were 3-ethyl-4-methyl-pentyl ester-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1), juglanoside E (2), (4S)-α-terpineol-8-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside (3), (4S)-α-terpineol-8-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (4), eugenyl-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (5), kaempferol-3-O-β-D-glucuronopyranosyl methylester (6), kaempferol-3-O-β-D-glucuronopyranoside (7), and quercetin-3-O-β-D-glucuronopyranoside (8).Among them, compound 1 was a new compound, and compounds 2-6 were isolated from the genus Cyclocarya for the first time.
- Cyclocarya paliurus,
- chemical constituents,
- glycoside,
- isolation and identification

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References

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