• 中国精品科技期刊
  • 中国高校百佳科技期刊
  • 中国中文核心期刊
  • 中国科学引文数据库核心期刊
Advanced Search
Synthesis and anti-platelet aggregation activity of substituted (E)-1，2-diarylethene compounds[J]. Journal of China Pharmaceutical University, 2010, 41(5): 419-423.
Citation: Synthesis and anti-platelet aggregation activity of substituted (E)-1，2-diarylethene compounds[J]. Journal of China Pharmaceutical University, 2010, 41(5): 419-423.
shu

Synthesis and anti-platelet aggregation activity of substituted (E)-1，2-diarylethene compounds

More Information
    Graphical Abstract
    • Abstract
  • Based on the analysis of the structure of diethyl 2-bromobenzylphosphonate，a series of substituted (E)-1，2-diarylethene compounds V1-V9 ， VI1-VI4 ) were synthesized，and their anti-platelet aggregation activities were evaluated.Their structures were confirmed by 1H NMR，IR and MS.It was found that most of the synthesized compounds possessed the anti-platelet aggregation activities，of which compounds V4 and V9 showed the most potent activities.Substituted(E)-1，2-diarylethene compounds are potentially new candidates as anti-platelet aggregation agents.〖
    • FullText(HTML)
    • References (0)
    • Related Articles

  • Related Articles

    [1]ZHU Hao, LIU Nan. Advances in research progress on acid tolerance mechanism of Gram- negative bacteria mediated by molecular chaperone protein[J]. Journal of China Pharmaceutical University, 2021, 52(2): 164-170. DOI: 10.11665/j.issn.1000-5048.20210204
    [2]LIU Zongliang, ZHANG Renmei, MENG Qingguo. Advances of targeting heat shock protein 70 drugs[J]. Journal of China Pharmaceutical University, 2017, 48(4): 416-424. DOI: 10.11665/j.issn.1000-5048.20170405
    [3]CHEN Ming, XIE Zhouling, LI Tinghan, WEI Zhihui, ZHAO Lu, LI Zhiyu. Advances in research on a novel antitumor target CDK9 and its inhibitors[J]. Journal of China Pharmaceutical University, 2017, 48(2): 233-241. DOI: 10.11665/j.issn.1000-5048.20170216
    [4]GAN Xia, NIAN Siyun, WANG Guoping. Advances in the development of farnesoid X receptor antagonists[J]. Journal of China Pharmaceutical University, 2016, 47(5): 521-530. DOI: 10.11665/j.issn.1000-5048.20160503
    [5]XIN Minhang, ZHANG Sanqi. Advances in PI3Kδ selective inhibitors[J]. Journal of China Pharmaceutical University, 2016, 47(5): 503-510. DOI: 10.11665/j.issn.1000-5048.20160501
    [6]HUANG Shaoliang, ZHAO Li, GUO Qinglong, WU Yulin. Advances of Hedgehog pathway in tumor resistance[J]. Journal of China Pharmaceutical University, 2016, 47(3): 259-266. DOI: 10.11665/j.issn.1000-5048.20160302
    [7]QI Likai, DI Bin. Advances in research on pharmaceutical impurities[J]. Journal of China Pharmaceutical University, 2015, 46(3): 257-263. DOI: 10.11665/j.issn.1000-5048.20150301
    [8]DENG Danni, TIAN Hong, YAO Wenbing. Advances in therapeutic B-cell vaccines against chronic diseases[J]. Journal of China Pharmaceutical University, 2013, 44(5): 470-475. DOI: 10.11665/j.issn.1000-5048.20130517
    [9]WANG Jing, ZHANG Hui-bin, ZHOU Jin-pei, LI Qing. Advances in new anti-tuberculosis targets and related drugs[J]. Journal of China Pharmaceutical University, 2012, 43(1): 1-8.
    [10]Advances in Selective COX-2 Inhibitors[J]. Journal of China Pharmaceutical University, 2003, (3): 1-6.

  • Cited by

    Periodical cited type(1)

    1. 杨中伟. 基于GC-MS法的毛发中苯丙胺类药物定性定量检测研究. 工业微生物. 2023(05): 57-59 .

    Other cited types(1)

Catalog

    Get Citation
    PDF
    XML
    Article views (1640) PDF downloads (2249) Cited by(2)
    Turn off MathJax
    Article Contents
    Abstract
    Related Articles

    Copyright © Journal of China Pharmaceutical University苏ICP备12050101号-2

    Address：24 Tongjia Lane, Nanjing City, Jiangsu Province （210009）Tel: 025-83271566E-mail: xuebao@cpu.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    Total visits：453280

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return