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Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae[J]. Journal of China Pharmaceutical University, 2010, 41(1): 50-54.
Citation: Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae[J]. Journal of China Pharmaceutical University, 2010, 41(1): 50-54.
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Application of internal standard correction method in the simultaneous determination of multi-components of Fructus Gardeniae

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  • Aim： To establish a simple and convenient quality evaluation method for Fructus Gardeniae(FG). Methods： The internal standard correction factors (fkm) of four crocetin derivatives to crocin-1 were established and the system suitability was tested.The content of crocin-1 was determined by external standard method，the contents of other crocetin derivatives were calculated by the content of crocin-1 and their fkm. Results： There was no significant difference between the test results obtained by the methods of “theoretical calculation by fkm” and “routire determination technique”. Conclusion： The internal standard correction method(the method of “theoretical calculation by fkm”) is practical and feasible in the quantitative analysis of Fructus Gardeniae.
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