Optimization of microwave extraction condition of<i> Gynura divaricata</i> polysaccharide by response surface analysis

ZHU Yasong; XU Wei; SHAO Rong; ZHU Yuezhao; Cheng Delin; LIAO Chuanhua

doi:10.11665/j.issn.1000-5048.20160319

Journal of China Pharmaceutical University > 2016 > 47(3): 359-362. > DOI: 10.11665/j.issn.1000-5048.20160319

ZHU Yasong, XU Wei, SHAO Rong, ZHU Yuezhao, Cheng Delin, LIAO Chuanhua. Optimization of microwave extraction condition of Gynura divaricata polysaccharide by response surface analysis[J]. Journal of China Pharmaceutical University, 2016, 47(3): 359-362. DOI: 10.11665/j.issn.1000-5048.20160319

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Optimization of microwave extraction condition of Gynura divaricata polysaccharide by response surface analysis

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Gynura divaricata polysaccharide was extracted from Gynura divaricata with the method of microwave-assisted extraction. Based on the results of single factor experiments, the extraction process was optimized by response surface analysis. The results indicated that the influencing factors during extraction were: liquid-solid ratio, microwave time, and microwave power, among which the influence of liquid-solid ratio was the most significant. The optimal conditions were as follows: liquid-solid ratio of 45∶1(mL/g), microwave power of 390 W, microwave time of 22 min. Under optimal extraction conditions, the extraction rate of Gynura divaricata polysaccharide was 15. 36%, which was pretty close to the predicted result. The optimized response surface methodology had some practical value for the process.
- Gynura divaricata,
- polysaccharide,
- microwave,
- response surface

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