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ZHU Yasong, XU Wei, SHAO Rong, ZHU Yuezhao, Cheng Delin, LIAO Chuanhua. Optimization of microwave extraction condition of Gynura divaricata polysaccharide by response surface analysis[J]. Journal of China Pharmaceutical University, 2016, 47(3): 359-362. DOI: 10.11665/j.issn.1000-5048.20160319
Citation: ZHU Yasong, XU Wei, SHAO Rong, ZHU Yuezhao, Cheng Delin, LIAO Chuanhua. Optimization of microwave extraction condition of Gynura divaricata polysaccharide by response surface analysis[J]. Journal of China Pharmaceutical University, 2016, 47(3): 359-362. DOI: 10.11665/j.issn.1000-5048.20160319
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Optimization of microwave extraction condition of Gynura divaricata polysaccharide by response surface analysis

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  • Gynura divaricata polysaccharide was extracted from Gynura divaricata with the method of microwave-assisted extraction. Based on the results of single factor experiments, the extraction process was optimized by response surface analysis. The results indicated that the influencing factors during extraction were: liquid-solid ratio, microwave time, and microwave power, among which the influence of liquid-solid ratio was the most significant. The optimal conditions were as follows: liquid-solid ratio of 45∶1(mL/g), microwave power of 390 W, microwave time of 22 min. Under optimal extraction conditions, the extraction rate of Gynura divaricata polysaccharide was 15. 36%, which was pretty close to the predicted result. The optimized response surface methodology had some practical value for the process.
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