Application of optical molecular imaging technology in the diagnosis and treatment of diseases

DONG Xue; GU Yueqing

doi:10.11665/j.issn.1000-5048.20140203

Journal of China Pharmaceutical University > 2014 > 45(2): 145-152. > DOI: 10.11665/j.issn.1000-5048.20140203

DONG Xue, GU Yueqing. Application of optical molecular imaging technology in the diagnosis and treatment of diseases[J]. Journal of China Pharmaceutical University, 2014, 45(2): 145-152. DOI: 10.11665/j.issn.1000-5048.20140203

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Application of optical molecular imaging technology in the diagnosis and treatment of diseases

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Abstract

Optical molecular imaging(OMI)is one of the rapidly developing biomedical imaging technique employing different technologies, such as optical molecular probing, imaging and nanotechnology to monitor a local real-time non-invasive qualitative or quantitative dynamic studies both in vivo and in vitro. OMT′s advantages, i. e. high sensitivity and specificity, especially in vivo studies, make it suitable for diagnosis, drug tracking in preclinical research and development of new drugs. Thus, it is regarded as a powerful real-time in vivo monitor. This paper discusses the latest advances in the use of fluorescent probes and nanomaterials in optical molecular imaging and its application in the diagnosis and treatment of diseases and in the studies of pharmacology and tumor biology.
- optical molecular imaging technology,
- diagnosis and treatment,
- mechanism,
- tumor biology,
- new drug research & development

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